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If everything is blocked / freezed, you can try this:
CTRL + ALT + F2
After this, you will be asked for your username and password to login. Type them then type this:
$ killall -u [your-username] gnome-session
That’s it. Of course all your unsaved data is lost !
If suddenly you have no sound on your ubuntu system, you should try this:
$ pulseaudio -k && sudo alsa force-reload
Also this should work:
$ killall pulseaudio